Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 3/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31190886 | 0.90 | AKT1 (0.42) | GRM2AKT1AKT2MAPK14KCNH2 | |
| SCHEMBL31191057 | 0.89 | MAPK14 (0.41) | GRM2AKT1AKT2MAPK14KCNH2 | |
| SCHEMBL31091926 | 0.83 | KDM4E (0.39) | GRM2AKT1AKT2MAPK14KCNH2 | |
| SCHEMBL31190929 | 0.83 | MAPK13 (0.39) | MAPK14KCNH2MAPK13 | |
| SCHEMBL31091889 | 0.82 | AKT1 (0.41) | GRM2AKT1AKT2NPC1RAB9A | |
| SCHEMBL31091869 | 0.82 | GRM2 (0.37) | GRM2AKT1AKT2MAPK14KCNH2 | |
| SCHEMBL31190904 | 0.82 | AKT1 (0.41) | GRM2AKT1AKT2KCNH2NPC1 | |
| SCHEMBL31298255 | 0.81 | KDM4E (0.36) | GRM2AKT1AKT2MAPK14KCNH2 | |
| SCHEMBL31190895 | 0.81 | AKT1 (0.40) | GRM2AKT1AKT2KCNH2NPC1 | |
| SCHEMBL31298251 | 0.80 | AKT1 (0.41) | AKT1AKT2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220543-A1 | NK3 MODULATORS AND USES THEREOF | KALLYOPE, INC. (US) | 2024-10-24 | — | — | WO | disclosed |