Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.52 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28799465 | 0.85 | KAT2B (0.55) | IDO1KAT2BMAPTL3MBTL1MAPK1 | |
| SCHEMBL5545632 | 0.83 | KAT2B (0.56) | IDO1KAT2BMAPTL3MBTL1MAPK1 | |
| SCHEMBL28219732 | 0.80 | MAPT (0.50) | IDO1KAT2BMAPTL3MBTL1MAPK1 | |
| SCHEMBL12914614 | 0.80 | KMT2A (0.50) | KAT2BMAPTL3MBTL1MAPK1SMN1; SMN2 | |
| SCHEMBL11658617 | 0.79 | KAT2B (0.49) | IDO1KAT2BMAPTL3MBTL1MAPK1 | |
| SCHEMBL985139 | 0.79 | KAT2B (0.55) | IDO1KAT2BMAPTL3MBTL1MAPK1 | |
| SCHEMBL9276000 | 0.78 | MAPT (0.51) | IDO1KAT2BMAPTL3MBTL1MAPK1 | |
| SCHEMBL162875 | 0.76 | KAT2B (0.60) | IDO1KAT2BMAPTL3MBTL1MAPK1 | |
| SCHEMBL13694754 | 0.76 | KAT2B (0.56) | IDO1KAT2BMAPTL3MBTL1MAPK1 | |
| SCHEMBL7745474 | 0.76 | KAT2B (0.60) | IDO1KAT2BMAPTL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113924296-B | 1,3, 4-Oxadiazole derivative compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions containing the same | 株式会社 钟根堂 | 2024-09-17 | — | — | CN | disclosed |