Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 5/20 | 0.57 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 4/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31193431 | 0.91 | TTR (0.59) | TTRPPARGPPARAALDH2MAOA | |
| SCHEMBL31193420 | 0.88 | TTR (0.51) | TTRMAOACSF1R | |
| SCHEMBL31193444 | 0.84 | TTR (0.61) | TTRALDH2MAOAKDM4EMEN1 | |
| SCHEMBL31193484 | 0.82 | TTR (0.53) | TTRMAOACSF1R | |
| SCHEMBL31193434 | 0.79 | TTR (0.62) | TTRALDH2MAOACSF1RKDM4E | |
| SCHEMBL27687212 | 0.78 | TTR (0.62) | TTRMAOACSF1RKDM4EALDH1A1 | |
| SCHEMBL31193425 | 0.78 | TTR (0.54) | TTRMAOACSF1RALDH1A1HPGD | |
| SCHEMBL31193467 | 0.77 | TTR (0.57) | TTRMAOACSF1RALDH1A1HPGD | |
| SCHEMBL31193359 | 0.74 | TTR (0.54) | TTRMAOACSF1R | |
| SCHEMBL4512899 | 0.73 | TTR (1.00) | TTRMAOAKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119118983-A | Xanthone compound and intermediate thereof, preparation method, pharmaceutical composition and application | 上海药坦药物研究开发有限公司 | 2024-12-13 | — | — | CN | claimed |
| CN-119118983-A | Xanthone compound and intermediate thereof, preparation method, pharmaceutical composition and application | 上海药坦药物研究开发有限公司 | 2024-12-13 | — | — | CN | disclosed |