Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 4/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.35 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31195009 | 1.00 | HDAC8 (0.39) | HDAC8HDAC6HDAC1HRH3HTR2C | |
| SCHEMBL31195026 | 1.00 | HDAC8 (0.39) | HDAC8HDAC6HDAC1HRH3HTR2C | |
| SCHEMBL31335269 | 1.00 | HDAC8 (0.39) | HDAC8HDAC6HDAC1HRH3HTR2C | |
| SCHEMBL31195030 | 1.00 | HDAC8 (0.39) | HDAC8HDAC6HDAC1HRH3HTR2C | |
| SCHEMBL31195005 | 1.00 | HDAC8 (0.39) | HDAC8HDAC6HDAC1HRH3HTR2C | |
| SCHEMBL31335451 | 0.80 | HRH3 (0.44) | HRH3GRIA4GRIA2FABP5SLC6A4 | |
| SCHEMBL31335235 | 0.79 | CYP2C9 (0.39) | HTR2CHTR2BKMT2AFABP5SLC6A4 | |
| SCHEMBL31335259 | 0.79 | CYP2C9 (0.39) | HTR2CHTR2BKMT2AFABP5SLC6A4 | |
| SCHEMBL31195069 | 0.78 | HTR2C (0.44) | HTR2CHTR2BSLC6A4SLC6A3KDM1A | |
| SCHEMBL31195001 | 0.78 | HTR2C (0.44) | HTR2CHTR2BSLC6A4SLC6A3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719605-A1 | CHEMICAL COMPOUNDS AND USES THEREOF | GlaxoSmithKline Intellectual Property (No.4) Limited (GB) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246863-A1 | CHEMICAL COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.4) LIMITED (GB) | 2024-12-05 | — | — | WO | disclosed |
| WO-2024246862-A1 | CHEMICAL COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 4) LIMITED (GB) | 2024-12-05 | — | — | WO | disclosed |