⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21576490 | 0.87 | NPSR1 (0.33) | — | |
| SCHEMBL25554244 | 0.87 | NPSR1 (0.33) | — | |
| SCHEMBL20690392 | 0.87 | NPSR1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL21570151 | 0.85 | NPSR1 (0.32) | — | |
| SCHEMBL30234161 | 0.75 | ATM (0.33) | — | |
| SCHEMBL20285870 | 0.73 | NPSR1 (0.34) | — | |
| SCHEMBL21496929 | 0.73 | MEN1 (0.32) | — | |
| SCHEMBL2340414 | 0.73 | NPSR1 (0.33) | — | |
| SCHEMBL2340412 | 0.73 | NPSR1 (0.33) | — | |
| SCHEMBL17064244 | 0.73 | NPSR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709716-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233554-A1 | ISOXAZOLIDINES AS RIPK1 INHIBITORS AND USE THEREOF | GENZYME CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |