Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 20/20 | 0.77 |
| ▸ | CX3CR1 | P49238 | 19/20 | 0.77 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23828012 | 1.00 | CXCR2 (0.77) | CXCR2CX3CR1HTR1BADORA1 | |
| SCHEMBL23828009 | 1.00 | CXCR2 (0.77) | CXCR2CX3CR1HTR1BADORA1 | |
| SCHEMBL213072 | 0.89 | CXCR2 (0.80) | CXCR2CX3CR1ADORA1 | |
| SCHEMBL23828030 | 0.88 | CXCR2 (0.61) | CXCR2CX3CR1HTR1BADORA1 | |
| SCHEMBL21615418 | 0.88 | CXCR2 (0.61) | CXCR2CX3CR1HTR1BADORA1 | |
| SCHEMBL213766 | 0.87 | CXCR2 (1.00) | CXCR2CX3CR1ADORA1 | |
| SCHEMBL4129653 | 0.87 | CXCR2 (1.00) | CXCR2CX3CR1ADORA1 | |
| SCHEMBL212748 | 0.87 | CXCR2 (1.00) | CXCR2CX3CR1ADORA1 | |
| SCHEMBL213886 | 0.87 | CXCR2 (1.00) | CXCR2CX3CR1ADORA1 | |
| SCHEMBL212230 | 0.87 | CXCR2 (0.73) | CXCR2CX3CR1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867725-B | Phosphate and phosphonate derivatives of 7-amino-5-thio-thiazolo [4,5-D ] pyrimidine modulators of CX3CR1 receptor and medical uses thereof | 坎塞拉有限公司 | 2024-09-27 | — | — | CN | disclosed |