Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.43 |
| ▸ | CNR1 | P21554 | 6/20 | 0.39 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.38 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21481780 | 0.91 | PTGER4 (0.38) | CNR2CNR1WNT3A | |
| SCHEMBL21458297 | 0.91 | PTGER4 (0.38) | CNR2CNR1WNT3A | |
| SCHEMBL31203156 | 0.88 | CNR2 (0.43) | CNR2CNR1BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL31203134 | 0.88 | CNR2 (0.43) | CNR2CNR1BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL31203155 | 0.87 | CNR2 (0.43) | CNR2CNR1BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL31203176 | 0.86 | CNR2 (0.42) | CNR2CNR1BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL31203150 | 0.86 | CNR2 (0.42) | CNR2CNR1BMPR1BBMPR1ATGFBR1 | |
| SCHEMBL22927215 | 0.84 | CNR2 (0.44) | CNR2CNR1 | |
| SCHEMBL31203357 | 0.84 | CNR2 (0.44) | CNR2CNR1 | |
| SCHEMBL31203411 | 0.84 | CNR2 (0.44) | CNR2CNR1BMPR1BBMPR1ATGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781550-B1 | BICYCLIC CARBOXAMIDES AND METHODS OF USE THEREOF | TEMPEST THERAPEUTICS INC (US) | 2024-10-30 | — | — | EP | claimed |