Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.40 |
| ▸ | CNR1 | P21554 | 7/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31203141 | 0.91 | CNR2 (0.37) | CNR2CNR1KDM4ELMNANPC1 | |
| SCHEMBL26616365 | 0.91 | CNR1 (0.39) | CNR2CNR1PDE7ASCN9AKDM4E | |
| SCHEMBL21458170 | 0.90 | PTGER4 (0.40) | CNR2CNR1PDE7ASCN9AKDM4E | |
| SCHEMBL31203157 | 0.85 | CNR2 (0.40) | CNR2CNR1 | |
| SCHEMBL21481783 | 0.84 | CNR1 (0.39) | CNR2CNR1PDE7AKDM4ENPC1 | |
| SCHEMBL22927215 | 0.84 | CNR2 (0.44) | CNR2CNR1 | |
| SCHEMBL31203357 | 0.84 | CNR2 (0.44) | CNR2CNR1 | |
| SCHEMBL31203142 | 0.83 | CNR2 (0.41) | CNR2CNR1KMT2A | |
| SCHEMBL31203156 | 0.82 | CNR2 (0.43) | CNR2CNR1 | |
| SCHEMBL21506723 | 0.82 | CNR2 (0.40) | CNR2CNR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781550-B1 | BICYCLIC CARBOXAMIDES AND METHODS OF USE THEREOF | TEMPEST THERAPEUTICS INC (US) | 2024-10-30 | — | — | EP | claimed |