Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 7/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31203142 | 0.91 | CNR2 (0.41) | CNR2MEN1KMT2ACNR1EPHX2 | |
| SCHEMBL31203160 | 0.91 | CNR2 (0.37) | CNR2MEN1KMT2ACNR1HDAC3 | |
| SCHEMBL21458209 | 0.90 | PTGER4 (0.44) | CNR2MEN1KMT2ACNR1HDAC3 | |
| SCHEMBL31203119 | 0.90 | PTGER4 (0.44) | CNR2MEN1KMT2ACNR1HDAC3 | |
| SCHEMBL21458254 | 0.89 | CYP3A4 (0.38) | CNR2MEN1KMT2ACNR1HDAC3 | |
| SCHEMBL31203148 | 0.88 | CNR2 (0.40) | CNR2MEN1KMT2ACNR1HDAC3 | |
| SCHEMBL26613243 | 0.84 | MEN1 (0.43) | CNR2MEN1KMT2ACNR1HDAC3 | |
| SCHEMBL21481757 | 0.82 | CNR1 (0.41) | CNR2MEN1KMT2ACNR1HDAC3 | |
| SCHEMBL21458214 | 0.80 | PTGER4 (0.47) | CNR2MEN1KMT2ACNR1EPHX2 | |
| SCHEMBL21458212 | 0.80 | PTGER4 (0.45) | CNR2MEN1KMT2ACNR1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781550-B1 | BICYCLIC CARBOXAMIDES AND METHODS OF USE THEREOF | TEMPEST THERAPEUTICS INC (US) | 2024-10-30 | — | — | EP | claimed |