Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 11/20 | 0.57 |
| ▸ | IKZF2 | Q9UKS7 | 7/20 | 0.50 |
| ▸ | WIZ | O95785 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984957 | 1.00 | CRBN (0.57) | CRBNIKZF2WIZCSNK1A1ESR1 | |
| SCHEMBL22498051 | 0.94 | CRBN (0.59) | CRBNIKZF2WIZCSNK1A1IKZF1 | |
| Hydrochloric Acid SCHEMBL30702602 | 0.94 | CRBN (0.54) | CRBNIKZF2WIZCSNK1A1IKZF1 | |
| Hydrochloric Acid SCHEMBL31726759 | 0.93 | CRBN (0.58) | CRBNIKZF2WIZCSNK1A1ESR1 | |
| Hydrochloric Acid SCHEMBL31204436 | 0.93 | CRBN (0.58) | CRBNIKZF2WIZCSNK1A1ESR1 | |
| SCHEMBL24571921 | 0.93 | CRBN (0.60) | CRBNIKZF2WIZCSNK1A1IKZF1 | |
| SCHEMBL27423664 | 0.93 | CRBN (0.60) | CRBNIKZF2WIZCSNK1A1IKZF1 | |
| SCHEMBL31027850 | 0.93 | CRBN (0.60) | CRBNIKZF2WIZCSNK1A1IKZF1 | |
| Hydrochloric Acid SCHEMBL25207279 | 0.92 | CRBN (0.59) | CRBNIKZF2WIZCSNK1A1IKZF1 | |
| Hydrochloric Acid SCHEMBL30423199 | 0.92 | CRBN (0.59) | CRBNIKZF2WIZCSNK1A1IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709486-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | Celgene Corporation (US) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024233748-A1 | HETEROARYL COMPOUNDS AS LIGAND DIRECTED DEGRADERS OF IRAK4 | CELGENE CORPORATION (US) | 2024-11-14 | — | — | WO | disclosed |