Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31217284 | 0.85 | GBA1 (0.46) | GBA1RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL2099047 | 0.80 | GBA1 (0.50) | GBA1RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL5734036 | 0.80 | GBA1 (0.50) | GBA1RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL9254369 | 0.78 | GBA1 (0.49) | GBA1RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL9279005 | 0.78 | GBA1 (0.52) | GBA1RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL17427745 | 0.75 | GBA1 (0.46) | GBA1RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL1181429 | 0.75 | GBA1 (0.42) | GBA1RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL29827507 | 0.75 | GBA1 (0.42) | GBA1RAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL6555780 | 0.74 | MAPT (0.44) | RAB9AALDH1A1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL23753449 | 0.71 | GBA1 (0.41) | GBA1RAB9ANPC1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4702021-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2026-03-04 | — | — | EP | disclosed |
| WO-2024224064-A1 | COMPOUNDS CAPABLE OF MODULATING GPR65 | Pathios Therapeutics Limited (GB) | 2024-10-31 | — | — | WO | disclosed |