Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 2/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31409932 | 1.00 | SMYD2 (0.36) | SMYD2GAATHRBSMN1; SMN2KLK7 | |
| SCHEMBL31409965 | 1.00 | SMYD2 (0.36) | SMYD2GAATHRBSMN1; SMN2KLK7 | |
| SCHEMBL15878429 | 1.00 | SMYD2 (0.36) | SMYD2GAATHRBSMN1; SMN2KLK7 | |
| SCHEMBL31207692 | 1.00 | SMYD2 (0.36) | SMYD2GAATHRBSMN1; SMN2KLK7 | |
| SCHEMBL14636814 | 0.87 | SRC (0.38) | SMYD2KLK7SRCMEN1KMT2A | |
| SCHEMBL31410012 | 0.87 | SRC (0.38) | SMYD2KLK7SRCMEN1KMT2A | |
| SCHEMBL14636816 | 0.87 | SRC (0.38) | SMYD2KLK7SRCMEN1KMT2A | |
| SCHEMBL17895054 | 0.87 | SRC (0.38) | SMYD2KLK7SRCMEN1KMT2A | |
| SCHEMBL31122923 | 0.85 | CYP1A2 (0.37) | SMYD2GAATHRBSMN1; SMN2KLK7 | |
| SCHEMBL30743026 | 0.85 | CYP1A2 (0.37) | SMYD2GAATHRBSMN1; SMN2KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3240543-B1 | BTK INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-11-06 | — | — | EP | disclosed |