SCHEMBL31208253

SCHEMBL31208253

CC(=O)N1CCc2c(c(Nc3ccc(Br)c(C(F)F)c3)nn2C2CCOCC2)C1

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CREBBP Q92793 20/20 0.68
▸ BRD4 O60885 19/20 0.68
▸ EP300 Q09472 3/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17795092 0.81 CREBBP (1.00) CREBBPBRD4EP300
SCHEMBL31208166 0.81 CREBBP (0.49) CREBBPBRD4
SCHEMBL31153556 0.80 BRD4 (0.62) CREBBPBRD4EP300
SCHEMBL31208234 0.79 CREBBP (0.43) CREBBPBRD4EP300
SCHEMBL17795192 0.78 CREBBP (1.00) CREBBPBRD4EP300
SCHEMBL21255123 0.77 CREBBP (0.67) CREBBPBRD4EP300
SCHEMBL34470810 0.77 CREBBP (0.60) CREBBPBRD4EP300
SCHEMBL17799456 0.76 CREBBP (0.47) CREBBPBRD4EP300
SCHEMBL34470809 0.76 CREBBP (0.52) CREBBPBRD4EP300
SCHEMBL17785786 0.76 BRD4 (0.74) CREBBPBRD4EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090330-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2026-04-30 — — WO disclosed
WO-2024220891-A1 COMPOUNDS AND USES THEREOF FOGHORN THERAPEUTICS INC. (US) 2024-10-24 — — WO disclosed
Send feedback