Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | JAK3 | P52333 | 4/20 | 0.41 |
| ▸ | JAK1 | P23458 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25232131 | 1.00 | DPP4 (0.41) | DPP4JAK3JAK1KMT2AKDM4E | |
| SCHEMBL20489593 | 0.84 | DPP4 (0.48) | DPP4KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL31208526 | 0.84 | DPP4 (0.44) | DPP4KMT2AKDM4EMEN1HSP90AA1 | |
| SCHEMBL25234713 | 0.84 | DPP4 (0.44) | DPP4KMT2AKDM4EMEN1HSP90AA1 | |
| SCHEMBL20330955 | 0.83 | DPP4 (0.54) | DPP4KMT2AMEN1GAATP53 | |
| SCHEMBL31208517 | 0.80 | IGF1R (0.43) | DPP4JAK3JAK1KMT2AKDM4E | |
| SCHEMBL3516119 | 0.79 | BAZ2B (0.49) | DPP4KMT2AKDM4EALDH1A1MEN1 | |
| SCHEMBL15689099 | 0.79 | POLB (0.49) | JAK3JAK1KMT2AKDM4EALDH1A1 | |
| SCHEMBL29613011 | 0.79 | POLB (0.49) | JAK3JAK1KMT2AKDM4EALDH1A1 | |
| SCHEMBL24341945 | 0.79 | CYP2C9 (0.50) | DPP4KMT2AKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118742542-A | Inhibitors of MET kinase | 金耐特生物制药公司 | 2024-10-01 | — | — | CN | disclosed |