Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31210905 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL3070688 | 0.93 | PREP (0.53) | — | |
| SCHEMBL3070690 | 0.93 | PREP (0.53) | — | |
| SCHEMBL3070684 | 0.93 | PREP (0.53) | — | |
| SCHEMBL1642226 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL19419802 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL31211088 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL28411733 | 0.81 | HTR2C (0.59) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL25841627 | 0.81 | HTR2C (0.59) | SMN1; SMN2NPC1RAB9AHTR2CCYP2C19 | |
| SCHEMBL13434443 | 0.81 | ACE2 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024182778-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2024-09-06 | — | — | WO | disclosed |