Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26100815 | 0.90 | TYK2 (0.51) | TYK2PDE4D | |
| SCHEMBL30392058 | 0.90 | TYK2 (0.53) | TYK2PDE4D | |
| SCHEMBL26101752 | 0.90 | TYK2 (0.53) | TYK2PDE4D | |
| SCHEMBL30392249 | 0.86 | TYK2 (0.51) | TYK2PDE4D | |
| SCHEMBL26101682 | 0.86 | TYK2 (0.51) | TYK2PDE4D | |
| SCHEMBL26102149 | 0.85 | TYK2 (0.55) | TYK2PDE4D | |
| SCHEMBL31218673 | 0.85 | TYK2 (0.38) | TYK2PDE4D | |
| SCHEMBL26098128 | 0.80 | TYK2 (0.39) | TYK2PDE4D | |
| SCHEMBL30392568 | 0.80 | TYK2 (0.36) | TYK2PDE4D | |
| SCHEMBL26100444 | 0.80 | TYK2 (0.36) | TYK2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013277-A | TYK2 degrading agent and application thereof | 凯麦拉医疗公司 | 2024-11-22 | — | — | CN | disclosed |