Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 9/20 | 0.45 |
| ▸ | EGFR | P00533 | 5/20 | 0.45 |
| ▸ | ABL1 | P00519 | 2/20 | 0.45 |
| ▸ | ABL2 | P42684 | 2/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31219370 | 0.92 | SRC (0.55) | SRCEGFRABL1ABL2 | |
| SCHEMBL31219364 | 0.92 | SRC (0.44) | SRCEGFRABL1ABL2RET | |
| SCHEMBL31219384 | 0.90 | SRC (0.39) | SRCEGFRABL1ABL2RET | |
| SCHEMBL31219429 | 0.88 | SRC (0.44) | SRCEGFRABL1ABL2RET | |
| SCHEMBL31219375 | 0.87 | SRC (0.53) | SRCEGFRABL1ABL2RET | |
| SCHEMBL31219398 | 0.86 | SRC (0.42) | SRCEGFRABL1ABL2RET | |
| SCHEMBL31219372 | 0.86 | SRC (0.43) | SRCEGFRABL1ABL2RET | |
| SCHEMBL31219363 | 0.86 | SRC (0.45) | SRCEGFRABL1ABL2RET | |
| SCHEMBL31219421 | 0.86 | SRC (0.43) | SRCEGFRABL1ABL2RET | |
| SCHEMBL31219361 | 0.85 | SRC (0.47) | SRCEGFRABL1ABL2RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013260-A | Spirobicyclic compounds | 优领医药科技(香港)有限公司 | 2024-11-22 | — | — | CN | disclosed |