Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3121175 | 0.85 | HRH1 (0.45) | SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL3120075 | 0.82 | EPHX2 (0.40) | SLC6A4 | |
| SCHEMBL26933620 | 0.81 | SLC7A5 (0.41) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL26933615 | 0.81 | SLC7A5 (0.41) | SLC6A4SLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL30636316 | 0.79 | SLC7A5 (0.40) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL2300932 | 0.79 | SCN9A (0.42) | — | |
| SCHEMBL12175595 | 0.79 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL14956613 | 0.79 | SLC6A2 (0.58) | SLC6A4SLC6A2SLC6A3HTR1A | |
| SCHEMBL30357881 | 0.79 | SLC6A2 (0.58) | SLC6A4SLC6A2SLC6A3HTR1A | |
| Hydrochloric Acid SCHEMBL30357928 | 0.77 | SLC6A2 (0.56) | SLC6A4SLC6A2SLC6A3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022055-A2 | INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | AMGEN INC. (US) | 2010-02-25 | — | — | WO | disclosed |