SCHEMBL31220008

SCHEMBL31220008

CC(C)(C)[Si](C)(C)OCc1cc2cnc(Cl)cc2cn1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
HDAC5 Q9UQL6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9941888 1.00 HDAC1 (0.32) HDAC1HDAC6HDAC5
SCHEMBL31219690 0.87 NPC1 (0.36)
SCHEMBL30107584 0.82
SCHEMBL20519187 0.82
SCHEMBL31658737 0.82 HDAC1 (0.31) HDAC1HDAC6HDAC5
SCHEMBL31219613 0.80
SCHEMBL20575319 0.80 HDAC1 (0.36) HDAC1HDAC6
SCHEMBL18900238 0.78 S1PR4 (0.38)
SCHEMBL18370221 0.78
SCHEMBL17979163 0.76 BACE1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4713096-A1 CDK INHIBITOR COMPOUNDS Aleksia Therapeutics, Inc. (US) 2026-03-25 EP disclosed
WO-2024238574-A1 CDK INHIBITOR COMPOUNDS ALEKSIA THERAPEUTICS, INC. (US) 2024-11-21 WO disclosed