SCHEMBL3122244

SCHEMBL3122244

CCCOc1csc(-c2ccc(OCCCOc3ccc4c(c3)CC[C@H]4CC(=O)O)c(OC)c2)n1

nearest known ligand 0.90

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.90
PPARA Q07869 20/20 0.90

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1400468 0.95 PPARD (1.00) PPARDPPARA
SCHEMBL1400402 0.94 PPARD (1.00) PPARDPPARA
SCHEMBL1400978 0.90 PPARD (1.00) PPARDPPARA
SCHEMBL1400497 0.90 PPARD (0.91) PPARDPPARA
SCHEMBL1400349 0.90 PPARD (1.00) PPARDPPARA
SCHEMBL1400323 0.89 PPARD (1.00) PPARDPPARA
SCHEMBL1400842 0.86 PPARD (1.00) PPARDPPARA
SCHEMBL1400331 0.86 PPARD (1.00) PPARDPPARA
SCHEMBL1400374 0.85 PPARD (1.00) PPARDPPARA
SCHEMBL1400573 0.85 PPARD (1.00) PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7714004-B2 Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation BAYER PHARMACEUTICALS CORPORATION (US) 2010-05-11 US claimed
EP-1578715-A2 INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION Bayer Pharmaceuticals Corporation (US) 2005-09-28 EP claimed
WO-2004058174-A2 INDANE ACETIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS, INTERMEDIATES, AND METHOD OF PREPARATION BAYER PHARMACEUTICALS CORPORATION (US) 2004-07-15 WO claimed