SCHEMBL31228127

SCHEMBL31228127

Cc1ncsc1-c1ccc([C@H](C)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCC(=O)O)C(C)(C)C)cc1

nearest known ligand 0.73

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ VHL P40337 13/20 0.73
▸ ELOC Q15369 2/20 0.73
▸ ELOB Q15370 2/20 0.73
▸ EGFR P00533 3/20 0.62
▸ BRD4 O60885 2/20 0.61
▸ NAMPT P43490 4/20 0.60
▸ HDAC3 O15379 1/20 0.60
▸ HDAC1 Q13547 1/20 0.60
▸ HDAC2 Q92769 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22325294 0.97 VHL (0.76) VHLELOCELOBEGFRBRD4
SCHEMBL22186170 0.97 VHL (0.76) VHLELOCELOBEGFRBRD4
SCHEMBL22186167 0.97 VHL (0.76) VHLELOCELOBEGFRBRD4
SCHEMBL24201266 0.97 VHL (0.76) VHLELOCELOBEGFRBRD4
SCHEMBL21308313 0.97 VHL (0.76) VHLELOCELOBEGFRBRD4
SCHEMBL24201263 0.97 VHL (0.76) VHLELOCELOBEGFRBRD4
SCHEMBL29290867 0.97 VHL (0.76) VHLELOCELOBEGFRBRD4
SCHEMBL23304123 0.96 VHL (0.67) VHLELOCELOBEGFRHDAC3
SCHEMBL23304120 0.96 VHL (0.67) VHLELOCELOBEGFRHDAC3
SCHEMBL24926153 0.96 VHL (0.67) VHLELOCELOBEGFRHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709370-A2 STAT DEGRADERS AND USES THEREOF Recludix Pharma, Inc. (US) 2026-03-18 — — EP disclosed
WO-2024233639-A2 STAT DEGRADERS AND USES THEREOF RECLUDIX PHARMA, INC. (US) 2024-11-14 — — WO disclosed
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