Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 16/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 15/20 | 0.44 |
| ▸ | ADK | P55263 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31228234 | 1.00 | PRMT5 (0.44) | PRMT5WDR77ADKPI4KAPI4K2B | |
| SCHEMBL22509892 | 1.00 | PRMT5 (0.44) | PRMT5WDR77ADKPI4KAPI4K2B | |
| SCHEMBL22509902 | 0.88 | PRMT5 (0.35) | PRMT5WDR77 | |
| SCHEMBL22799458 | 0.83 | PRMT5 (0.43) | PRMT5WDR77ADKPI4KAPI4K2B | |
| SCHEMBL21122799 | 0.83 | PRMT5 (0.43) | PRMT5WDR77ADKPI4KAPI4K2B | |
| SCHEMBL22707788 | 0.83 | PRMT5 (0.43) | PRMT5WDR77ADKPI4KAPI4K2B | |
| SCHEMBL22799339 | 0.83 | PRMT5 (0.43) | PRMT5WDR77ADKPI4KAPI4K2B | |
| SCHEMBL22495075 | 0.82 | PRMT5 (0.40) | PRMT5WDR77ADKRAPGEF3 | |
| SCHEMBL25806907 | 0.82 | PRMT5 (0.46) | PRMT5WDR77ADKRAPGEF3 | |
| SCHEMBL24090721 | 0.81 | PRMT5 (0.42) | PRMT5WDR77ADKRAPGEF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705313-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | The Scripps Research Institute (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024227159-A2 | 4'-SUBSTITUTED NUCLEOSIDES AND NUCLEOTIDES AS ANTIVIRAL AGENTS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2024-10-31 | — | — | WO | disclosed |