Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 10/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL831895 | 0.99 | RPS6KA2 (0.42) | RPS6KA2ECE1F10PTGDR2MAOB | |
| SCHEMBL833601 | 0.92 | ECE1 (0.42) | RPS6KA2ECE1F10PTGDR2MAOB | |
| SCHEMBL832105 | 0.79 | ECE1 (0.41) | ECE1F10PTGDR2MAOBABCB1 | |
| SCHEMBL3148861 | 0.79 | MAOB (0.50) | ECE1F10PTGDR2MAOBABCB1 | |
| SCHEMBL831603 | 0.78 | ECE1 (0.41) | ECE1F10PTGDR2MAOBABCB1 | |
| SCHEMBL3158981 | 0.77 | ECE1 (0.47) | ECE1F10PTGDR2MAOB | |
| SCHEMBL3150006 | 0.77 | MAOB (0.49) | ECE1F10MAOB | |
| SCHEMBL3153583 | 0.77 | ECE1 (0.48) | ECE1F10PTGDR2MAOBABCB1 | |
| SCHEMBL833415 | 0.76 | MAOB (0.45) | ECE1F10PTGDR2MAOBABCB1 | |
| SCHEMBL3158442 | 0.76 | TP53 (0.48) | ECE1F10MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1987010-B1 | TRICYCLIC N-HETEROARYL-CARBOXAMIDE DERIVATIVES CONTAINING A BENZIMIDAZOLE UNIT, METHOD FOR PREPARING SAME AND THEIR THERAPEUTIC USE | SANOFI AVENTIS (FR) | 2010-04-07 | — | — | EP | disclosed |