Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 1.00 |
| ▸ | NPC1 | O15118 | 5/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | MAOB | P27338 | 2/20 | 0.76 |
| ▸ | MAOA | P21397 | 1/20 | 0.76 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | CTSL | P07711 | 2/20 | 0.57 |
| ▸ | CTSB | P07858 | 2/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25221774 | 1.00 | MAPT (1.00) | MAPTNPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL25207340 | 1.00 | MAPT (1.00) | MAPTNPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL30383257 | 1.00 | MAPT (1.00) | MAPTNPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL25185070 | 0.89 | MAPT (0.80) | MAPTNPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL25214347 | 0.89 | MAPT (0.80) | MAPTNPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL30382973 | 0.89 | MAPT (0.80) | MAPTNPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL21749655 | 0.85 | MAOB (1.00) | MAPTNPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL2327949 | 0.85 | HDAC4 (0.77) | MAPTNPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL25200446 | 0.85 | MAPT (0.74) | MAPTNPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL25216238 | 0.85 | MAPT (0.74) | MAPTNPC1RAB9AL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024233598-A1 | COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS | YewSavin, Inc. (US) | 2024-11-14 | — | — | WO | disclosed |