Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 5/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.48 |
| ▸ | IKBKB | O14920 | 1/20 | 0.47 |
| ▸ | NQO2 | P16083 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31237875 | 0.86 | CYP1A1 (0.66) | APPKDM4ESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL13446070 | 0.82 | APP (0.95) | APPKDM4ESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL24860541 | 0.81 | KDM4E (0.66) | APPKDM4ESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL14705615 | 0.80 | APP (0.91) | APPKDM4ESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL1181273 | 0.80 | APP (1.00) | APPKDM4ESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL23566334 | 0.80 | NQO2 (0.71) | APPALDH1A1HPGDLMNAPRSS1 | |
| SCHEMBL14705443 | 0.78 | APP (0.95) | APPKDM4ESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL23566269 | 0.78 | PLAU (0.50) | KDM4ESMN1; SMN2NPC1ALDH1A1GLA | |
| SCHEMBL31237168 | 0.77 | APP (0.54) | APPKDM4ESMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL2544746 | 0.77 | KDM4E (0.69) | APPKDM4ESMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024189607-A1 | METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT | DIDENKO KIRILL (MX) | 2024-09-19 | — | — | WO | disclosed |