Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | JAK2 | O60674 | 8/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | TYK2 | P29597 | 2/20 | 0.42 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.41 |
| ▸ | CDK2 | P24941 | 3/20 | 0.41 |
| ▸ | CDC7 | O00311 | 2/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.40 |
| ▸ | PAK4 | O96013 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240378 | 0.89 | JAK2 (0.51) | JAK2LRRK2TYK2JAK3JAK1 | |
| SCHEMBL31240716 | 0.87 | JAK2 (0.54) | JAK2LRRK2TYK2JAK3JAK1 | |
| SCHEMBL31240512 | 0.83 | JAK2 (0.52) | JAK2LRRK2TYK2JAK3JAK1 | |
| SCHEMBL31240406 | 0.82 | JAK2 (0.60) | JAK2LRRK2TYK2JAK3MAPK1 | |
| SCHEMBL31240555 | 0.82 | JAK2 (0.55) | JAK2LRRK2TYK2JAK3MAP4K4 | |
| SCHEMBL26685748 | 0.82 | JAK2 (0.55) | JAK2LRRK2TYK2JAK3MAP4K4 | |
| SCHEMBL26686310 | 0.82 | JAK2 (0.55) | JAK2LRRK2TYK2JAK3MAP4K4 | |
| SCHEMBL31240411 | 0.81 | CDC7 (0.58) | JAK2LRRK2TYK2JAK3JAK1 | |
| SCHEMBL31240692 | 0.80 | LRRK2 (0.54) | JAK2LRRK2TYK2JAK3JAK1 | |
| SCHEMBL31240674 | 0.80 | JAK2 (0.48) | JAK2LRRK2TYK2JAK3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |