Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 7/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.46 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.42 |
| ▸ | CDC7 | O00311 | 2/20 | 0.42 |
| ▸ | PLK4 | O00444 | 2/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.42 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | CDK1 | P06493 | 2/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | MARK3 | P27448 | 2/20 | 0.42 |
| ▸ | CLK2 | P49760 | 2/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.42 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240674 | 0.89 | JAK2 (0.48) | JAK2MAPK12MAP4K4DYRK1ACDC7 | |
| SCHEMBL31240447 | 0.89 | JAK2 (0.48) | JAK2MAPK12MAP4K4DYRK1ACDC7 | |
| SCHEMBL31240406 | 0.89 | JAK2 (0.60) | JAK2MAPK12MAP4K4DYRK1ACDC7 | |
| SCHEMBL31240716 | 0.89 | JAK2 (0.54) | JAK2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL31240275 | 0.86 | LRRK2 (0.47) | JAK2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL31240440 | 0.86 | JAK2 (0.45) | JAK2MAPK14MAPK12MAP4K4DYRK1A | |
| SCHEMBL31240422 | 0.85 | JAK2 (0.49) | JAK2MAPK12MAP4K4DYRK1ACDC7 | |
| SCHEMBL31240513 | 0.83 | PIM1 (0.50) | JAK2DYRK1ACDC7CDK2CLK2 | |
| SCHEMBL31240512 | 0.83 | JAK2 (0.52) | JAK2MAPK14MAPK13MAPK12MAP4K4 | |
| SCHEMBL31240555 | 0.82 | JAK2 (0.55) | JAK2MAPK14MAPK12MAP4K4DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |