Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 4/20 | 0.48 |
| ▸ | CDK2 | P24941 | 4/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.47 |
| ▸ | CLK2 | P49760 | 6/20 | 0.47 |
| ▸ | CLK3 | P49761 | 4/20 | 0.47 |
| ▸ | JAK2 | O60674 | 6/20 | 0.43 |
| ▸ | EGFR | P00533 | 5/20 | 0.42 |
| ▸ | JAK3 | P52333 | 3/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.42 |
| ▸ | PRKACA | P17612 | 3/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.42 |
| ▸ | AURKA | O14965 | 2/20 | 0.42 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.42 |
| ▸ | PRKCG | P05129 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31240622 | 0.90 | DYRK1A (0.48) | CDC7CDK2CCNE1DBF4DYRK1A | |
| SCHEMBL31240570 | 0.86 | DYRK1A (0.48) | CDC7CDK2CCNE1DBF4DYRK1A | |
| SCHEMBL31240411 | 0.86 | CDC7 (0.58) | CDC7CDK2CCNE1DBF4DYRK1A | |
| SCHEMBL31240405 | 0.85 | CLK2 (0.59) | DYRK1ACLK2CLK3JAK2EGFR | |
| SCHEMBL31240700 | 0.85 | CLK2 (0.58) | DYRK1ACLK2CLK3JAK2JAK3 | |
| SCHEMBL31240550 | 0.85 | DYRK1A (0.51) | CDC7CDK2CCNE1DBF4DYRK1A | |
| SCHEMBL31240503 | 0.84 | PRMT5 (0.47) | CDC7CDK2CCNE1DBF4DYRK1A | |
| SCHEMBL31240301 | 0.83 | DYRK1A (0.46) | CDC7CDK2CCNE1DBF4DYRK1A | |
| SCHEMBL31240357 | 0.83 | DYRK1A (0.45) | CDC7CDK2CCNE1DBF4DYRK1A | |
| SCHEMBL31240343 | 0.81 | CLK2 (0.63) | DYRK1ACLK2CLK3JAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | claimed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |