Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK3 | P27361 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.58 |
| ▸ | KRAS | P01116 | 16/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29321614 | 0.94 | MAPK3 (0.57) | MAPK3MAPK1KRAS | |
| SCHEMBL30873477 | 0.94 | MAPK3 (0.57) | MAPK3MAPK1KRAS | |
| SCHEMBL31382660 | 0.94 | MAPK3 (0.55) | MAPK3MAPK1KRAS | |
| SCHEMBL30873456 | 0.94 | KRAS (0.59) | MAPK3MAPK1KRAS | |
| SCHEMBL31527344 | 0.94 | KRAS (0.59) | MAPK3MAPK1KRAS | |
| SCHEMBL29321556 | 0.94 | KRAS (0.59) | MAPK3MAPK1KRAS | |
| SCHEMBL31382816 | 0.94 | KRAS (0.59) | MAPK3MAPK1KRAS | |
| SCHEMBL30873385 | 0.92 | KRAS (0.60) | MAPK3MAPK1KRAS | |
| SCHEMBL29321623 | 0.92 | KRAS (0.60) | MAPK3MAPK1KRAS | |
| SCHEMBL30873418 | 0.92 | KRAS (0.56) | MAPK3MAPK1KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4713330-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF | HUTCHMED Limited (CN) | 2026-03-25 | — | — | EP | disclosed |
| WO-2024235286-A1 | TRICYCLIC COMPOUNDS AND USES THEREOF | HUTCHMED LIMITED (CN) | 2024-11-21 | — | — | WO | disclosed |