Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 6/20 | 0.48 |
| ▸ | WNT1 | P04628 | 4/20 | 0.48 |
| ▸ | GSK3B | P49841 | 10/20 | 0.47 |
| ▸ | GSK3A | P49840 | 9/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.44 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26129618 | 1.00 | DYRK1A (0.48) | DYRK1AWNT1GSK3BGSK3AFGFR1 | |
| SCHEMBL26394767 | 0.86 | GSK3B (0.56) | DYRK1AWNT1GSK3BGSK3APIM1 | |
| Hydrochloric Acid SCHEMBL26130060 | 0.86 | GSK3B (0.55) | DYRK1AWNT1GSK3BGSK3APIM1 | |
| SCHEMBL26395369 | 0.85 | GSK3B (0.55) | DYRK1AWNT1GSK3BGSK3A | |
| Hydrochloric Acid SCHEMBL26131872 | 0.85 | GSK3B (0.54) | DYRK1AWNT1GSK3BGSK3A | |
| SCHEMBL26395169 | 0.85 | DYRK1A (0.55) | DYRK1AWNT1GSK3BGSK3APIK3CD | |
| SCHEMBL31243456 | 0.84 | GSK3B (0.52) | DYRK1AWNT1GSK3BGSK3APIK3CD | |
| SCHEMBL26131806 | 0.84 | GSK3B (0.52) | DYRK1AWNT1GSK3BGSK3APIK3CD | |
| SCHEMBL26395355 | 0.84 | GSK3A (0.53) | DYRK1AWNT1GSK3BGSK3APIK3CD | |
| Hydrochloric Acid SCHEMBL31243406 | 0.84 | DYRK1A (0.54) | DYRK1AWNT1GSK3BGSK3APIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118974020-A | Substituted 3-aminoindazole derivatives as kinase inhibitors | 内尔维亚诺医疗科学公司 | 2024-11-15 | — | — | CN | claimed |
| CN-118974020-A | Substituted 3-aminoindazole derivatives as kinase inhibitors | 内尔维亚诺医疗科学公司 | 2024-11-15 | — | — | CN | disclosed |