Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 2/20 | 0.33 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL312179 | 0.92 | MAOB (0.39) | MAOBCYP1A2CYP2C9CYP2C19ELANE | |
| SCHEMBL312054 | 0.87 | MAOB (0.39) | MAOBCYP1A2CYP2C9CYP2C19ELANE | |
| SCHEMBL313600 | 0.85 | MAOB (0.41) | MAOBCYP1A2CYP2C9CYP2C19ELANE | |
| SCHEMBL312716 | 0.84 | MAOB (0.43) | MAOBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL311390 | 0.84 | AKR1B1 (0.41) | MAOBCYP1A2CYP2C9CYP2C19ELANE | |
| SCHEMBL312259 | 0.84 | MAOB (0.40) | MAOBCYP1A2CYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL312485 | 0.83 | HPGD (0.39) | MAOBCYP1A2CYP2C9CYP2C19ELANE | |
| SCHEMBL311904 | 0.82 | HPGD (0.40) | MAOBCYP1A2CYP2C9CYP2C19ELANE | |
| SCHEMBL311757 | 0.81 | MAOB (0.39) | MAOBCYP1A2CYP2C9CYP2C19ELANE | |
| SCHEMBL312471 | 0.81 | AKR1B1 (0.40) | MAOBCYP1A2CYP2C9CYP2C19ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093273-B2 | Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2012-01-10 | — | — | US | disclosed |
| EP-2332527-A2 | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases | RESVERLOGIX CORP. (CA) | 2011-06-15 | — | — | EP | disclosed |