Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 19/20 | 0.40 |
| ▸ | HTR2B | P41595 | 17/20 | 0.40 |
| ▸ | HTR2A | P28223 | 17/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31244681 | 0.77 | HTR2C (0.43) | HTR2CHTR2BHTR2A | |
| SCHEMBL31245175 | 0.77 | HTR2C (0.43) | HTR2CHTR2BHTR2A | |
| SCHEMBL31245348 | 0.77 | HTR2C (0.43) | HTR2CHTR2BHTR2A | |
| SCHEMBL24675511 | 0.77 | HTR2C (0.41) | HTR2CHTR2BHTR2A | |
| SCHEMBL29841889 | 0.77 | HTR2C (0.41) | HTR2CHTR2BHTR2A | |
| SCHEMBL24674723 | 0.77 | HTR2A (0.51) | HTR2CHTR2BHTR2A | |
| SCHEMBL24763593 | 0.77 | HTR2C (0.41) | HTR2CHTR2BHTR2A | |
| SCHEMBL24675008 | 0.77 | HTR2C (0.43) | HTR2CHTR2BHTR2A | |
| SCHEMBL24639880 | 0.76 | HRH3 (0.31) | — | |
| SCHEMBL31244630 | 0.75 | HTR2C (0.40) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240336629-A1 | Tricyclic Derivatives Useful As PARP7 Inhibitors | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2024-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240336629-A1 | Tricyclic Derivatives Useful As PARP7 Inhibitors | PARP1, PARP2, PARP11 | HTR2C 1125/4885HTR2B 726/4885HTR2A 1918/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.