SCHEMBL31246014

SCHEMBL31246014

Cc1ccc(S(=O)(=O)n2ccc3c(-c4cc(C(C)(C)O)ccc4OC4CC(N(C)CCN5CCNCC5)C4)cn(C)c(=O)c32)cc1

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 19/20 0.42
▸ HDAC1 Q13547 3/20 0.37
▸ HDAC6 Q9UBN7 2/20 0.37
▸ HTR6 P50406 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30824906 0.90 BRD4 (0.43) BRD4HDAC1HDAC6
SCHEMBL30812303 0.84 BRD4 (0.45) BRD4HDAC1HDAC6
SCHEMBL30812284 0.84 BRD4 (0.46) BRD4HDAC1HDAC6
SCHEMBL30812154 0.82 BRD4 (0.41) BRD4HDAC1HDAC6HTR6
SCHEMBL30812019 0.81 BRD4 (0.41) BRD4HDAC1HDAC6HTR6
SCHEMBL31245971 0.81 BRD4 (0.48) BRD4
SCHEMBL30812323 0.80 BRD4 (0.44) BRD4HDAC1HDAC6
SCHEMBL30812177 0.80 BRD4 (0.43) BRD4HDAC1HDAC6
SCHEMBL30812157 0.80 BRD4 (0.52) BRD4HTR6
SCHEMBL30824888 0.78 BRD4 (0.52) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4702022-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE Halda Therapeutics Opco, Inc. (US) 2026-03-04 — — EP disclosed
US-20260028338-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE HALDA THERAPEUTICS OPCO INC (US) 2026-01-29 — — US disclosed
WO-2024211684-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE HALDA THERAPEUTICS OPCO, INC. (US) 2024-10-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028338-A1 HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, HCCS BRD4 479/4885HDAC1 233/4885HDAC6 161/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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