SCHEMBL3124622

SCHEMBL3124622

C=CCCCCCC(C#N)CCCC

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.56
ALDH1A1 P00352 4/20 0.48
USP2 O75604 2/20 0.34
MAPT P10636 2/20 0.34
CYP3A4 P08684 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TRPA1 O75762 1/20 0.33
PTGS1 P23219 1/20 0.33
PPARG P37231 1/20 0.33
OPRK1 P41145 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
DNM1 Q05193 1/20 0.32
LMNA P02545 1/20 0.32
ABCC4 O15439 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3112778 1.00 TSHR (0.56) TSHRALDH1A1USP2MAPTCYP3A4
SCHEMBL3118524 1.00 TSHR (0.56) TSHRALDH1A1USP2MAPTCYP3A4
SCHEMBL3108944 0.98 TSHR (0.52) TSHRALDH1A1USP2MAPTCYP3A4
SCHEMBL31590958 0.96 TSHR (0.61) TSHRALDH1A1USP2MAPTCYP3A4
SCHEMBL4354554 0.96 TSHR (0.61) TSHRALDH1A1USP2MAPTCYP3A4
SCHEMBL3127320 0.92 TSHR (0.50) TSHRALDH1A1USP2MAPTCYP3A4
SCHEMBL3108005 0.92 TSHR (0.50) TSHRALDH1A1USP2MAPTCYP3A4
SCHEMBL3112131 0.92 TSHR (0.50) TSHRALDH1A1USP2MAPTCYP3A4
SCHEMBL3124535 0.92 TSHR (0.52) TSHRALDH1A1SMN1; SMN2DNM1
Benzene SCHEMBL27880268 0.91 TSHR (0.55) TSHRALDH1A1USP2MAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117756986-A Cycloolefin copolymer, preparation method thereof, cycloolefin copolymer hydride and optical material 杭州睿丰融创科技有限公司 2024-03-26 CN claimed
CN-117756986-A Cycloolefin copolymer, preparation method thereof, cycloolefin copolymer hydride and optical material 杭州睿丰融创科技有限公司 2024-03-26 CN disclosed
CN-116496446-B Norbornene hydrogenated ring-opening polymer, preparation method thereof and optical material 杭州睿丰融创科技有限公司 2024-03-22 CN disclosed
CN-116496446-A Norbornene hydrogenated ring-opening polymer, preparation method thereof and optical material 杭州睿丰融创科技有限公司 2023-07-28 CN disclosed
US-7714087-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2010-05-11 US disclosed
EP-1734061-B1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer and uses thereof MITSUI CHEMICALS INC (JP) 2010-04-07 EP disclosed
US-20090137757-A1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof IMUTA JUNICHI 2009-05-28 US disclosed
US-7393907-B2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2008-07-01 US disclosed
CN-100357330-C Polar group-containing olefin copolymer, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS INC (JP) 2007-12-26 CN disclosed
CN-100335509-C Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS INC (JP) 2007-09-05 CN disclosed
CN-1737017-A Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS INC (JP) 2006-02-22 CN disclosed
CN-1737016-A Polar group-containing olefin copolymer, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS INC (JP) 2006-02-22 CN disclosed
CN-1219800-C Polar group-containing olefin copolymer, thermoplastic resin composition containing the same, and use thereof MITSUI CHEMICALS INC (JP) 2005-09-21 CN disclosed
CN-1342715-A Polar group-containing olefin copolymer, process for producing the same, thermoplastic resin composition containing the same, and use thereof MITSUI CHEMICALS INC (JP) 2002-04-03 CN disclosed