SCHEMBL31246277

CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)C(C)(C)NC(=O)[C@H](Cc1ccc(O)cc1)NC)[C@@H](C)O)[C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NC(C)(C)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CCC(N)=O)C(=O)NC(C)(C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@](C)(CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(N)=O)C(C)C

nearest known ligand 0.74

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	17/20	0.74

▸	CCKBR	P32239	4/20	0.74

▸	GCGR	P47871	10/20	0.71

▸	GIPR	P48546	7/20	0.71

▸	NPY1R	P25929	1/20	0.65

▸	NPY2R	P49146	1/20	0.65

▸	NPY4R	P50391	1/20	0.65

▸	NPY5R	Q15761	1/20	0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL31246303	0.97	GLP1R (0.77)	GLP1RCCKBRGCGRGIPR
SCHEMBL31246274	0.97	GLP1R (0.69)	GLP1RCCKBRGCGRGIPRNPY1R
SCHEMBL31246278	0.97	GLP1R (0.69)	GLP1RCCKBRGCGRGIPRNPY1R
SCHEMBL31246279	0.95	GLP1R (0.71)	GLP1RCCKBRGCGRGIPRNPY1R
SCHEMBL31246306	0.94	GLP1R (0.72)	GLP1RCCKBRGCGRGIPR
SCHEMBL31246294	0.94	GLP1R (0.72)	GLP1RCCKBRGCGRGIPR
SCHEMBL31246305	0.92	GLP1R (0.75)	GLP1RCCKBRGCGRGIPR
SCHEMBL30881331	0.90	GLP1R (0.79)	GLP1RCCKBRGCGRGIPR
SCHEMBL29364819	0.90	GLP1R (0.81)	GLP1RCCKBRGCGRGIPR
SCHEMBL31246276	0.89	GIPR (0.75)	GLP1RGCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3601329-B1	GIP RECEPTOR ACTIVATING PEPTIDE	TAKEDA PHARMACEUTICALS CO (JP)	2024-12-04	—	—	EP	claimed
EP-3601329-B1	GIP RECEPTOR ACTIVATING PEPTIDE	TAKEDA PHARMACEUTICALS CO (JP)	2024-12-04	—	—	EP	disclosed