Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12264971 | 0.84 | MEN1 (0.63) | HRH4HRH1NSD2PKMMEN1 | |
| SCHEMBL23579730 | 0.81 | HRH1 (0.48) | HRH4HRH1NSD2PKMMEN1 | |
| SCHEMBL30033960 | 0.81 | HRH1 (0.48) | HRH4HRH1NSD2PKMMEN1 | |
| SCHEMBL7655764 | 0.77 | NSD2 (0.75) | NSD2PKMMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL31249014 | 0.76 | KMT2A (0.53) | HRH4HRH1NSD2PKMMEN1 | |
| SCHEMBL31248990 | 0.76 | KMT2A (0.48) | HRH4HRH1NSD2PKMMEN1 | |
| SCHEMBL23579990 | 0.75 | KMT2A (0.45) | HRH4HRH1NSD2PKMMEN1 | |
| SCHEMBL28855535 | 0.74 | KMT2A (0.47) | HRH4HRH1NSD2PKMMEN1 | |
| SCHEMBL14071906 | 0.72 | PIK3CA (0.62) | — | |
| SCHEMBL10307718 | 0.71 | PDE2A (0.43) | HRH4HRH1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719388-A2 | COVALENT INHIBITORS AS ANTI-MALARIAL AGENTS | Purdue Research Foundation (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024249604-A2 | COVALENT INHIBITORS AS ANTI-MALARIAL AGENTS | PURDUE RESEARCH FOUNDATION (US) | 2024-12-05 | — | — | WO | disclosed |