Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21460991 | 1.00 | MAP3K5 (1.00) | MAP3K5 | |
| SCHEMBL21461208 | 0.94 | MAP3K5 (1.00) | MAP3K5 | |
| SCHEMBL21461149 | 0.94 | MAP3K5 (1.00) | MAP3K5 | |
| SCHEMBL31248973 | 0.94 | MAP3K5 (1.00) | MAP3K5 | |
| SCHEMBL21469802 | 0.90 | MAP3K5 (1.00) | MAP3K5 | |
| SCHEMBL21461155 | 0.90 | MAP3K5 (1.00) | MAP3K5 | |
| SCHEMBL21461140 | 0.90 | MAP3K5 (1.00) | MAP3K5 | |
| SCHEMBL21461032 | 0.89 | MAP3K5 (1.00) | MAP3K5 | |
| SCHEMBL21461116 | 0.89 | MAP3K5 (1.00) | MAP3K5 | |
| SCHEMBL21461061 | 0.84 | MAP3K5 (1.00) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4537902-A2 | TRICYCLIC ASK1 INHIBITORS | Terns, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| EP-3773577-B1 | TRICYCLIC ASK1 INHIBITORS | TERNS INC (US) | 2024-11-20 | — | — | EP | disclosed |