Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 4/20 | 0.67 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.67 |
| ▸ | RET | P07949 | 1/20 | 0.67 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.67 |
| ▸ | MARK3 | P27448 | 1/20 | 0.67 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.67 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.67 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.67 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.67 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.67 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.67 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.67 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.67 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.67 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.67 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.67 |
| ▸ | STK26 | Q9P289 | 1/20 | 0.67 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.67 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.67 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31250747 | 0.88 | FGFR1 (0.75) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL31250962 | 0.87 | FGFR1 (0.69) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL31250907 | 0.85 | FGFR1 (0.71) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL62562 | 0.85 | FGFR1 (0.82) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL31251043 | 0.82 | FGFR1 (0.66) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL13574162 | 0.82 | FGFR1 (0.77) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL13574146 | 0.82 | FGFR1 (0.77) | FGFR1NTRK1RETPDGFRBMARK3 | |
| SCHEMBL63830 | 0.82 | FGFR1 (0.77) | FGFR1NTRK1RETPDGFRBMARK3 | |
| Fexagratinib SCHEMBL15250892 | 0.81 | FGFR1 (1.00) | FGFR1NTRK1RETPDGFRBMARK3 | |
| Azd-4547 SCHEMBL22132858 | 0.81 | FGFR1 (1.00) | FGFR1NTRK1RETPDGFRBMARK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720058-A2 | BIFUNCTIONAL DEGRADERS AND USES THEREOF | Casma Therapeutics, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024249291-A2 | BIFUNCTIONAL DEGRADERS AND USES THEREOF | CASMA THERAPEUTICS, INC. (US) | 2024-12-05 | — | — | WO | disclosed |