Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | GLA | P06280 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19492616 | 0.88 | CYP1A2 (0.48) | NPC1RAB9ASMN1; SMN2TP53RXFP1 | |
| SCHEMBL19492487 | 0.83 | KDM4E (0.48) | NPC1RAB9ASMN1; SMN2TP53RXFP1 | |
| SCHEMBL18805714 | 0.81 | MALT1 (0.48) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL17293115 | 0.79 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2TP53RXFP1 | |
| SCHEMBL18787721 | 0.77 | MALT1 (0.44) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL25375133 | 0.74 | CSNK1D (0.49) | NPC1RAB9ASMN1; SMN2TP53KMT2A | |
| SCHEMBL239039 | 0.74 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2TP53RXFP1 | |
| SCHEMBL19464210 | 0.74 | KDM4E (0.48) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL18787731 | 0.74 | MALT1 (0.52) | NPC1RAB9ASMN1; SMN2TP53KDM4E | |
| SCHEMBL31208517 | 0.74 | IGF1R (0.43) | NPC1RAB9ASMN1; SMN2TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720058-A2 | BIFUNCTIONAL DEGRADERS AND USES THEREOF | Casma Therapeutics, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024249291-A2 | BIFUNCTIONAL DEGRADERS AND USES THEREOF | CASMA THERAPEUTICS, INC. (US) | 2024-12-05 | — | — | WO | disclosed |