Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL31252190 | 0.81 | HTT (0.36) | HTTKAT2BTGM2KEAP1NFE2L2 | |
| Bromide SCHEMBL31252086 | 0.80 | HTT (0.46) | HTTKAT2BTGM2KEAP1NFE2L2 | |
| SCHEMBL31252012 | 0.79 | HTT (0.55) | HTTKAT2BTGM2KEAP1NFE2L2 | |
| Bromide SCHEMBL31252188 | 0.78 | HTT (0.34) | HTTTGM2KEAP1NFE2L2SMN1; SMN2 | |
| Bromide SCHEMBL31252103 | 0.70 | HTT (0.46) | HTTKAT2BTGM2KEAP1NFE2L2 | |
| Bromide SCHEMBL31252155 | 0.69 | HTT (0.46) | HTTKAT2BTGM2KEAP1NFE2L2 | |
| Bromide SCHEMBL31252065 | 0.69 | HTT (0.46) | HTTKAT2BTGM2KEAP1NFE2L2 | |
| Bromide SCHEMBL31252066 | 0.69 | HTT (0.46) | HTTKAT2BTGM2KEAP1NFE2L2 | |
| SCHEMBL31252144 | 0.69 | HTT (0.54) | HTTKAT2BTGM2KEAP1NFE2L2 | |
| SCHEMBL31252088 | 0.67 | HTT (0.54) | HTTKAT2BTGM2KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720162-A1 | MAIN CHAIN CATIONIC OLIGO(IMIDAZOLIUM) FORMS N-HETEROCYCLIC CARBENE FOR EFFECTIVE BACTERIAL KILLING IN COMPLEX ENVIRONMENT | Nanyang Technological University (SG) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024248739-A1 | MAIN CHAIN CATIONIC OLIGO(IMIDAZOLIUM) FORMS N-HETEROCYCLIC CARBENE FOR EFFECTIVE BACTERIAL KILLING IN COMPLEX ENVIRONMENT | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2024-12-05 | — | — | WO | disclosed |