SCHEMBL31255464

SCHEMBL31255464

CCOC(=O)Cn1cc(C=O)cn1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
JAK1 P23458 6/20 0.43
JAK2 O60674 4/20 0.43
GSK3A P49840 1/20 0.42
GSK3B P49841 1/20 0.42
TYK2 P29597 4/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MAPK1 P28482 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
JAK3 P52333 1/20 0.39
MITF O75030 1/20 0.39
PIN1 Q13526 1/20 0.39
PIN4 Q9Y237 1/20 0.39
KDM4E B2RXH2 3/20 0.39
HPGD P15428 2/20 0.39
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18183184 0.86 SYK (0.36) ALDH1A1JAK1JAK2SMN1; SMN2NPC1
SCHEMBL12124191 0.82 ALPI (0.49) ALDH1A1JAK1JAK2GSK3AGSK3B
SCHEMBL12890169 0.82 KDM4E (0.39) ALDH1A1JAK1JAK2GSK3BNPC1
SCHEMBL18623452 0.79 GSK3A (0.44) ALDH1A1JAK1JAK2GSK3AGSK3B
SCHEMBL12968057 0.79 GSK3A (0.44) ALDH1A1JAK1JAK2GSK3AGSK3B
SCHEMBL14125781 0.79 GSK3A (0.44) ALDH1A1JAK1JAK2GSK3AGSK3B
SCHEMBL14663783 0.79 SMN1; SMN2 (0.47) ALDH1A1JAK1JAK2GSK3AGSK3B
SCHEMBL14125630 0.79 GSK3A (0.44) ALDH1A1JAK1JAK2GSK3AGSK3B
SCHEMBL14149257 0.79 SMN1; SMN2 (0.44) ALDH1A1JAK1JAK2GSK3AGSK3B
SCHEMBL5965015 0.78 HTT (0.37) ALDH1A1KDM4EHPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720044-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD Beactica Therapeutics AB (SE) 2026-04-08 EP disclosed
WO-2024240840-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD BEACTICA THERAPEUTICS AB (SE) 2024-11-28 WO disclosed