SCHEMBL31255533

SCHEMBL31255533

Cc1ccc(OCC(=O)N2CCC(C(=O)N3CCC(C(=O)OC(C)(C)C)CC3)CC2)cc1N1CCC(=O)NC1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DDB1 Q16531 3/20 0.44
▸ CRBN Q96SW2 3/20 0.44
▸ TSHR P16473 2/20 0.41
▸ MAPT P10636 2/20 0.41
▸ MAPK1 P28482 2/20 0.41
▸ TP53 P04637 1/20 0.41
▸ SMN1; SMN2 Q16637 3/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ RAB9A P51151 1/20 0.40
▸ KMT2A Q03164 3/20 0.40
▸ LMNA P02545 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ FKBP1A P62942 1/20 0.39
▸ ALDH1A1 P00352 3/20 0.39
▸ KDM4E B2RXH2 2/20 0.39
▸ HPGD P15428 2/20 0.39
▸ HSD17B10 Q99714 2/20 0.39
▸ GAA P10253 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38
▸ MEN1 O00255 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31255338 0.90 CRBN (0.42) DDB1CRBNTSHRMAPTSMN1; SMN2
SCHEMBL31255217 0.89 KDM4E (0.49) DDB1CRBNMAPTSMN1; SMN2RAB9A
SCHEMBL31255223 0.88 DDB1 (0.47) DDB1CRBNTSHRMAPTMAPK1
SCHEMBL31255237 0.87 DDB1 (0.45) DDB1CRBNTSHRMAPTMAPK1
SCHEMBL31255205 0.85 POLB (0.52) DDB1CRBNMAPTSMN1; SMN2RAB9A
Trifluoroacetic Acid SCHEMBL31255377 0.85 DDB1 (0.42) DDB1CRBNMAPTSMN1; SMN2RAB9A
SCHEMBL31255309 0.84 DDB1 (0.49) DDB1CRBNMAPTSMN1; SMN2RAB9A
SCHEMBL31255634 0.80 DDB1 (0.47) DDB1CRBNMAPTSMN1; SMN2RAB9A
SCHEMBL31040960 0.80 DDB1 (0.65) DDB1CRBNTSHRTP53SMN1; SMN2
SCHEMBL31255571 0.80 DDB1 (0.48) DDB1CRBNTSHRMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720044-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD Beactica Therapeutics AB (SE) 2026-04-08 — — EP disclosed
WO-2024240840-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD BEACTICA THERAPEUTICS AB (SE) 2024-11-28 — — WO disclosed
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