SCHEMBL31255712

SCHEMBL31255712

O=C1CCC(N2C(=O)c3cccc(N4CCC(OC5CCNCC5)CC4)c3C2=O)C(=O)N1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 19/20 0.57
DDB1 Q16531 17/20 0.57
IKZF3 Q9UKT9 3/20 0.57
TNF P01375 1/20 0.57
IL1B P01584 1/20 0.57
TBXA2R P21731 1/20 0.57
IKZF1 Q13422 1/20 0.57
ALDH1A1 P00352 1/20 0.54
CHRM2 P08172 1/20 0.54
OPRM1 P35372 1/20 0.54
CYP1A2 P05177 1/20 0.54
TSHR P16473 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
HPGDS O60760 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30938334 0.89 CRBN (0.59) CRBNDDB1IKZF3TNFIL1B
SCHEMBL31255472 0.89 CRBN (0.60) CRBNDDB1IKZF3TNFIL1B
SCHEMBL19586913 0.89 CRBN (0.65) CRBNDDB1IKZF3TNFIL1B
SCHEMBL21997283 0.88 DDB1 (0.53) CRBNDDB1IKZF3TNFIL1B
Hydrochloric Acid SCHEMBL20294525 0.88 CRBN (0.64) CRBNDDB1IKZF3TNFIL1B
SCHEMBL31255255 0.87 CRBN (0.59) CRBNDDB1IKZF3TNFIL1B
SCHEMBL31129334 0.86 DDB1 (0.57) CRBNDDB1IKZF3TNFIL1B
SCHEMBL24820815 0.85 CRBN (0.58) CRBNDDB1IKZF3TNFIL1B
SCHEMBL30993710 0.85 CRBN (0.62) CRBNDDB1IKZF3TNFIL1B
SCHEMBL23788120 0.85 CRBN (0.57) CRBNDDB1IKZF3TNFIL1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720044-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD Beactica Therapeutics AB (SE) 2026-04-08 EP disclosed
WO-2024240840-A1 AROMATIC AMIDES AND CONJUGATES THEREOF AS BINDERS TO TEAD BEACTICA THERAPEUTICS AB (SE) 2024-11-28 WO disclosed