Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31258243 | 0.79 | KDM1A (0.39) | KDM1AHTR2CHTR2BRCOR1SLC6A2 | |
| SCHEMBL8629822 | 0.78 | TSHR (0.37) | KDM1AHTR2BKMT2AMEN1CYP2C19 | |
| SCHEMBL30954421 | 0.78 | TSHR (0.37) | KDM1AHTR2BKMT2AMEN1CYP2C19 | |
| SCHEMBL31258231 | 0.76 | HTR2C (0.48) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| SCHEMBL31258197 | 0.71 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20562175 | 0.71 | KDM1A (0.43) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| SCHEMBL18312348 | 0.71 | KDM1A (0.43) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| SCHEMBL27319350 | 0.70 | KDM1A (0.53) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| SCHEMBL31258158 | 0.69 | HTR2C (0.39) | KDM1AHTR2AHTR2CHTR2BRCOR1 | |
| SCHEMBL1893123 | 0.68 | KDM1A (0.47) | KDM1AHTR2AHTR2CHTR2BRCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119039312-A | Method for preparing medical intermediate 3-benzimidazoline coumarin pyranone derivative by catalyzing acid eutectic solvent | 南京欣久医药科技有限公司 | 2024-11-29 | — | — | CN | disclosed |