Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23980143 | 0.83 | SSTR4 (0.46) | LMNASMN1; SMN2HTTTP53ALDH1A1 | |
| SCHEMBL2527064 | 0.83 | HPGD (0.47) | LMNASMN1; SMN2HTTALDH1A1 | |
| Hydrochloric Acid SCHEMBL31258455 | 0.83 | SMN1; SMN2 (0.51) | LMNASMN1; SMN2HTTALDH1A1HSD17B10 | |
| SCHEMBL951538 | 0.80 | KMT2A (0.59) | SMN1; SMN2HTTL3MBTL1ALDH1A1MAPT | |
| SCHEMBL31258454 | 0.79 | SMN1; SMN2 (0.53) | LMNASMN1; SMN2HTTALDH1A1MAPT | |
| SCHEMBL16095344 | 0.79 | KMT2A (0.60) | LMNASMN1; SMN2HTTL3MBTL1THRB | |
| SCHEMBL19716850 | 0.79 | KMT2A (0.58) | LMNASMN1; SMN2HTTL3MBTL1THRB | |
| SCHEMBL2855372 | 0.78 | KDM4E (0.57) | SMN1; SMN2HTTL3MBTL1ALDH1A1MAPT | |
| SCHEMBL304546 | 0.76 | SMN1; SMN2 (0.58) | SMN1; SMN2HTTL3MBTL1MAPTMAPK1 | |
| SCHEMBL14376547 | 0.76 | HTT (0.53) | SMN1; SMN2HTTL3MBTL1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4700019-A1 | CRYSTAL FORM OF 1,5-DIHYDRO-2,4-BENZODIAZEPINE-3-ONE DERIVATIVE CITRATE, PREPARATION METHOD, AND USE THEREOF | Jiangsu NHWA Pharmaceutical Co., Ltd (CN) | 2026-02-25 | — | — | EP | disclosed |
| WO-2024217521-A1 | CRYSTAL FORM OF 1,5-DIHYDRO-2,4-BENZODIAZEPINE-3-ONE DERIVATIVE CITRATE, PREPARATION METHOD, AND USE THEREOF | 江苏恩华药业股份有限公司 | 2024-10-24 | — | — | WO | disclosed |