Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 14/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 14/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 13/20 | 0.34 |
| ▸ | TSHR | P16473 | 10/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 7/20 | 0.34 |
| ▸ | LMNA | P02545 | 7/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 5/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.32 |
| ▸ | USP2 | O75604 | 5/20 | 0.32 |
| ▸ | PDE9A | O76083 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31258700 | 0.95 | CYP1A2 (0.35) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL31258637 | 0.92 | CYP1A2 (0.34) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL25260600 | 0.88 | PDE9A (0.34) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL30462758 | 0.88 | PDE9A (0.34) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL31258657 | 0.84 | CYP1A2 (0.36) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL30462730 | 0.82 | PDE9A (0.35) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL25299300 | 0.82 | PDE9A (0.35) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL31258707 | 0.82 | CYP1A2 (0.35) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL31258641 | 0.81 | CYP1A2 (0.32) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 | |
| SCHEMBL25257429 | 0.79 | PDE9A (0.35) | CYP1A2CYP3A4CYP2C19TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118715231-A | Complement factor inhibitors and uses thereof | 安尼艾克松股份有限公司 | 2024-09-27 | — | — | CN | disclosed |