Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23538061 | 1.00 | CCR1 (0.46) | CCR1CCR5CCR8KIF11METAP2 | |
| Hydrochloric Acid SCHEMBL30917887 | 1.00 | CCR1 (0.46) | CCR1CCR5CCR8KIF11METAP2 | |
| Bromide SCHEMBL29619590 | 0.98 | CCR1 (0.44) | CCR1CCR5CCR8KIF11METAP2 | |
| SCHEMBL347025 | 0.98 | CCR1 (0.48) | CCR1CCR5CCR8KIF11METAP2 | |
| SCHEMBL29373631 | 0.98 | CCR1 (0.48) | CCR1CCR5CCR8KIF11METAP2 | |
| SCHEMBL29453375 | 0.98 | CCR1 (0.48) | CCR1CCR5CCR8KIF11METAP2 | |
| SCHEMBL117845 | 0.95 | CCR1 (0.46) | CCR1CCR5CCR8KIF11METAP2 | |
| SCHEMBL2783812 | 0.95 | CCR1 (0.46) | CCR1CCR5CCR8KIF11METAP2 | |
| SCHEMBL335953 | 0.95 | CCR1 (0.46) | CCR1CCR5CCR8KIF11METAP2 | |
| Lithium SCHEMBL31260758 | 0.95 | CCR1 (0.46) | CCR1CCR5CCR8KIF11METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120202211-A | Cyclic compounds having selective KRAS inhibition over HRAS and NRAS | 中外制药株式会社 | 2025-06-24 | — | — | CN | disclosed |
| CN-119823103-A | Polycyclic derivative inhibitor, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2025-04-15 | — | — | CN | disclosed |
| CN-118974035-A | 2-Aminoimidazole derivatives as PRMT5 inhibitors | 米拉蒂医疗股份有限公司 | 2024-11-15 | — | — | CN | disclosed |