Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MPO | P05164 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.62 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | HTR1B | P28222 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16007455 | 1.00 | TACR1 (0.64) | TACR1MAPTKDM4EMEN1LMNA | |
| SCHEMBL30852356 | 1.00 | TACR1 (0.64) | TACR1MAPTKDM4EMEN1LMNA | |
| SCHEMBL2123774 | 1.00 | TACR1 (0.64) | TACR1MAPTKDM4EMEN1LMNA | |
| SCHEMBL1167928 | 1.00 | TACR1 (0.64) | TACR1MAPTKDM4EMEN1LMNA | |
| Hydrochloric Acid SCHEMBL1167927 | 0.99 | TACR1 (0.62) | TACR1MAPTKDM4EMEN1LMNA | |
| Hydrochloric Acid SCHEMBL18185314 | 0.99 | TACR1 (0.62) | TACR1MAPTKDM4EMEN1LMNA | |
| Hydrochloric Acid SCHEMBL1167925 | 0.99 | TACR1 (0.62) | TACR1MAPTKDM4EMEN1LMNA | |
| SCHEMBL6423830 | 0.96 | TACR1 (0.62) | TACR1MAPTKDM4EMEN1LMNA | |
| SCHEMBL12966393 | 0.96 | TACR1 (0.62) | TACR1MAPTKDM4EMEN1LMNA | |
| SCHEMBL6423829 | 0.96 | TACR1 (0.62) | TACR1MAPTKDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024243289-A2 | GUT MICROBE DERIVED AROMATIC AMINO ACID METABOLITES FOR DETECTION AND TREATMENT OF DISEASE | THE CLEVELAND CLINIC FOUNDATION (US) | 2024-11-28 | — | — | WO | disclosed |