Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | PDE5A | O76074 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31259643 | 0.85 | CCNC (0.47) | ERN1ALDH1A1POLBMAPTCDK2 | |
| SCHEMBL31259726 | 0.82 | CA12 (0.46) | ERN1ALDH1A1POLBMAPTCDK2 | |
| SCHEMBL17680435 | 0.82 | CYP19A1 (0.55) | ERN1ALDH1A1POLBAURKAMAPT | |
| SCHEMBL17794965 | 0.80 | AURKA (0.41) | ERN1ALDH1A1AURKAMEN1KMT2A | |
| SCHEMBL31259710 | 0.79 | AURKA (0.43) | AURKACDK2CCNA2TTKBRD4 | |
| SCHEMBL17806596 | 0.77 | AURKA (0.39) | ERN1AURKACDK2CCNA2TTK | |
| SCHEMBL17680442 | 0.76 | ERN1 (0.49) | ERN1ALDH1A1POLBAURKAMAPT | |
| SCHEMBL1571809 | 0.76 | ERN1 (0.55) | ERN1ALDH1A1POLBAURKAMEN1 | |
| SCHEMBL1571428 | 0.73 | ERN1 (0.52) | ERN1ALDH1A1POLBAURKAMAPT | |
| SCHEMBL16055423 | 0.73 | ERN1 (0.46) | ERN1ALDH1A1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024254527-A1 | METHODS OF TREATING INFLAMMATORY DISEASES | INTERLINE THERAPEUTICS, INC. (US) | 2024-12-12 | — | — | WO | disclosed |