SCHEMBL31260547

SCHEMBL31260547

O=C(N[C@@H](Cc1cc(Br)c(O)c(Br)c1)C(=O)O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 3/20 0.52
▸ TP53 P04637 3/20 0.52
▸ MDM2 Q00987 4/20 0.49
▸ SLC17A5 Q9NRA2 1/20 0.48
▸ CASP3 P42574 2/20 0.47
▸ EPHX2 P34913 1/20 0.47
▸ PTPN1 P18031 1/20 0.46
▸ TLR2 O60603 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3962011 1.00 MDM4 (0.52) MDM4TP53MDM2SLC17A5CASP3
SCHEMBL21192398 1.00 MDM4 (0.52) MDM4TP53MDM2SLC17A5CASP3
SCHEMBL4151914 0.91 MDM4 (0.51) MDM4TP53MDM2SLC17A5CASP3
SCHEMBL31520527 0.91 EPHX2 (0.46) MDM4TP53MDM2SLC17A5CASP3
SCHEMBL14060944 0.90 MDM4 (0.50) MDM4TP53MDM2SLC17A5CASP3
SCHEMBL30898978 0.90 MDM4 (0.50) MDM4TP53MDM2SLC17A5CASP3
SCHEMBL120691 0.87 MDM4 (0.52) MDM4TP53MDM2SLC17A5CASP3
SCHEMBL29401272 0.87 MDM4 (0.52) MDM4TP53MDM2SLC17A5CASP3
SCHEMBL30898983 0.87 MDM4 (0.49) MDM4TP53MDM2SLC17A5CASP3
SCHEMBL1228254 0.86 MDM4 (0.59) MDM4TP53MDM2SLC17A5CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4732286-A2 COMPOSITIONS AND METHODS FOR ENCRYPTING, STORING, AND DECRYPTING INFORMATION IN OLIGOMERS Board of Regents, The University of Texas System (US) 2026-04-29 — — EP disclosed
US-20260036595-A1 STRUCTURE-BASED PEPTIDES FOR DETECTION OF TRANSTHYRETIN AMYLOID FIBRILS AND AGGREGATES IN PREECLAMPSIA THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2026-02-05 — — US disclosed
US-20250362310-A1 STRUCTURE-BASED PROBE FOR DETECTION OF TRANSTHYRETIN AMYLOID FIBRILS AND AGGREGATES THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-11-27 — — US disclosed
WO-2025058677-A2 COMPOSITIONS AND METHODS FOR ENCRYPTING, STORING, AND DECRYPTING INFORMATION IN OLIGOMERS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-03-20 — — WO disclosed
US-20240360178-A1 MACROCYCLIC IMMUNOMODULATORS BRISTOL-MYERS SQUIBB COMPANY 2024-10-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240360178-A1 MACROCYCLIC IMMUNOMODULATORS CD274, PDCD1LG2, PDCD1 MDM4 1128/4885TP53 158/4885MDM2 757/4885
US-20260036595-A1 STRUCTURE-BASED PEPTIDES FOR DETECTION OF TRANSTHYRETIN AMYLOID FIBRILS AND AGGREGATES IN PREECLAMPSIA TTR, APP, SERPINA3 MDM4 2595/4885TP53 940/4885MDM2 2792/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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